Selected Publications
- Maternal PRDM10 activates essential genes for oocyte-to-embryo transition. Michelle K.Y. Seah, Brenda Y. Han, Yan Huang, Louise J.H. Rasmussen, Andrina J. Stäubli, Judith Bello-Rodríguez, Andrew Chi Ho Chan, Maxime Gasnier, Heike Wollmann, Ernesto Guccione, Daniel M. Messerschmidt. Nature Communications
- Discovery of a Potent and Selective Protein Arginine Methyltransferase 5 (PRMT5) PROTAC Degrader. Yue Zhong, Huensuk Kim, Chao Qian, Ling Xie, Xian Chen, Yan Xiong, Jacqueline Hu, Matthew Chen, Ernesto Guccione, Yudao Shen, Jian Jin. Journal of Medicinal Chemistry
- Unveiling sequence-agnostic mixed-chemical modification patterns for splice-switching oligonucleotides using the NATURA platform. Tommaso Tabaglio, Taniya Agarwal, Wei Yuan Cher, Jin Rong Ow, Ah Keng Chew, Priscila Yun Qian Sun, Raja Sekhar Reddy Gurrampati, Hongfang Lu, Praveena Naidu, Hong Kai Ng, Xavier Le Guezennec, Shi Yan Ng, Manikandan Lakshmanan, Ernesto Guccione, Keng Boon Wee. Molecular Therapy Nucleic Acids