Selected Publications

• Integrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer’s disease. Phoebe Valdes, Andrew B. Caldwell, Qing Liu, Michael Q. Fitzgerald, Srinivasan Ramachandran, Celeste M. Karch, Xiong Xu, Jinbin Xu, Chengjie Xiong, Elise Weamer, Qing Wang, Peter Wang, Jonathan Vöglein, Sarah Thompson, Kevin Taddei, Sochenda Stephens, Hamid Sohrabi, Beth Snitz, Lori Smith, Jennifer Smith, Wendy Sigurdson, Hiroyuki Shimada, Kristine Shady, Nicholas T. Seyfried, Michio Senda, Peter Schofield, Stephen Salloway, John Ringman, Alan Renton, Oliver Preische, Lingyan Ping, Richard Perrin, Riddhi Patira, Antoinette O’Connor, Ulricke Obermüller, Brigitte Nuscher, Joanne Norton, James Noble, Yoshiki Niimi, Katie Neimeyer, Akemi Nagamatsu, Neelesh Nadkarni, Cath Mummery, James Mountz, John Morris, Estrella Morenas-Rodriguez, Arlene Mejia, Eric McDade, Austin McCullough, Alison Goate. Alzheimer's Research and Therapy
• Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia. Jorge J. Llibre-Guerra, M. Victoria Fernandez, Nelly Joseph-Mathurin, Shijia Bian, Kathleen Carter, Yan Li, Andrew J. Aschenbrenner, Cyril Pottier, Wendy Sigurdson, Eric McDade, Brian A. Gordon, Alan E. Renton, Tammie L.S. Benzinger, Laura Ibañez, Nico Barthelemy, Matthew Johnson, Jason Hassenstab, Guoqiao Wang, Alison M. Goate, Dan Western, Ciyang Wang, Diana Hobbs, Alisha Daniels, Celeste Karch, John C. Morris, Carlos Cruchaga, Erik C.B. Johnson, Randall J. Bateman, Ellen Ziegemeier, Angela Ziegemeier, Jinbin Xu, Xiong Xu, Chengjie Xiong, Yong Wang, Qing Wang, Jonathan Vöglein, Andrei Vlassenko, Silvia Vazquez, Reda Timofejavaite, Ezequiel Surace, Charlene Supnet-Bell, Sarah Stout, Jennifer Stauber, Jennifer Smith, Karina Skrbec, Ashlee Simmons, Nicholas T. Seyfried, Laura Serna, Michio Senda, Brian Fulton-Howard. Nature Medicine
• CASP8 intronic expansion identified by poly-glycine-arginine pathology increases Alzheimer’s disease risk. Lien Nguyen, Ramadan Ajredini, Shu Guo, Lisa E.L. Romano, Rodrigo F. Tomas, Logan R. Bell, Paul T. Ranum, Tao Zu, Monica Bañez Coronel, Chase P. Kelley, Javier Redding-Ochoa, Evangelos Nizamis, Alexandra Melloni, Theresa R. Connors, Angelica Gaona, Kiruphagaran Thangaraju, Olga Pletnikova, H. Brent Clark, Beverly L. Davidson, Anthony T. Yachnis, Todd E. Golde, Xiang Yang Lou, Eric T. Wang, Alan E. Renton, Alison Goate, Paul N. Valdmanis, Stefan Prokop, Juan C. Troncoso, Bradley T. Hyman, Laura P.W. Ranum. Proceedings of the National Academy of Sciences of the United States of America